Dr. Badr Saleh, a teacher at the Faculty of Pharmacy, received his Doctorate with his tagged thesis (Design) And the manufacture of new isotopes of nucleosides as possible antiviral hepatitis C) from the University of Toledo American. The thesis addressed viral hepatitis despite progress in the treatment of Patients with hepatitis C, but it is still an important cause of liver disease due to its nature The thesis aims to seek a comprehensive cure for the disease because of the presence of seven genetic types of virus and many subtypes, which in many cases may lead to the use of multiple treatments to counter Disease. The thesis concluded the discovery of several points to disrupt the life cycle of the virus and stop the manufacture of proteins. Viral, which contributed to the discovery of effective antiviral treatments, including the identification of the crystalline composition of viral protein NS5B, because it's the machine for the production of viral DNA, and this viral protein has been selected. as a goal for the design and development of antivirals because it is not present in humans and because the effective location in This protein is preserved in various genetic types of hepatitis C virus. In this thesis was manufactured 2- C- Uredine acetylcholine and 2-C-(1-hydroxy ethyl) uredine are expected to give these compounds Bioactive anti-hepatitis C virus and may be developed in the form of drugs in the future
