The College of Education for Pure Sciences researched a doctoral thesis on the evaluation of oxidative stress and lipid profile in patients with polycystic ovary syndrome in Basrah Governorate.
The thesis submitted by the researcher (Ashwaq Aboud Shanta) included this study to measure hormonal and biochemical indicators for 100 women with polycystic ovary syndrome (PCOS) and 80 healthy women. Hormone levels (LH, FSH, PRL), oxidative stress indicators, antioxidants, vitamins (A, E, C), trace minerals (copper, zinc, selenium), and lipid profile (total cholesterol, triglycerides, HDL, LDL, VLDL), in addition to hemoglobin and ferritin were measured.
The participants were divided into categories based on blood type, age, marital status, and body mass index, to study the effect of these factors on biochemical indicators in both the PCOS group and the control group.
The results showed a significant increase (P < 0.0001) in the levels of LH, PRL, copper, harmful lipids (TC, TG, LDL, VLDL), ferritin, and hemoglobin in women with PCOS, while a decrease was observed in the levels of FSH, antioxidants, vitamins A, E, C, zinc, selenium, and HDL. The study also revealed that obesity and age exacerbate the biochemical imbalances, as some hormones and harmful lipids increase with age, while antioxidants and vitamins decrease. The data were analyzed using SPSS V.23, and the correlation coefficient was used to determine the differences and statistical significance between the two groups.
