A Doctoral Thesis at the University of Basra Explores Therapeutic Role of Green Biosynthetic Nanoparticles
A doctoral dissertation from the College of Veterinary Medicine at the University of Basra investigated the therapeutic potential of green biosynthetic nanoparticles synthesized using isoflavonoid extract from Ginkgo biloba in the treatment of glucocorticoid-induced osteoporosis.
Presented by researcher Ayat Rahman Subaih, the study aimed to assess the effects of these nanoparticles on various physiological, histological, molecular, and biochemical parameters following the induction of osteoporosis with dexamethasone (DXM) in adult male rats.
The findings revealed that the biosynthetic nanoparticles demonstrated superior therapeutic efficacy compared to both the Ginkgo biloba isoflavonoid extract and vitamin D. Improvements were observed in physiological and molecular markers, along with reduced tissue damage.
The thesis recommended further exploration of chemical nanoparticles, investigation of estrogen levels before and after menopause in women, and evaluation of Ginkgo biloba extract as a potential anti-cancer treatment.
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