A Master’s thesis at the College of Veterinary Medicine, University of Basrah, focused on the molecular diagnosis of Proteus mirabilis isolated from humans and companion animals.
The study, conducted by Msc student Hussein Ali Nasser, aimed to isolate and diagnose this bacterium from human, cat, and dog samples using both conventional and molecular methods.
The research centered on analyzing four major virulence genes (ureC, hpmA, mrpA, and ureR) to detect genetic diversity and single nucleotide polymorphisms (SNPs) in comparison with a reference strain.
The results revealed significant genetic diversity among the local isolate.
Several SNPs were identified that may influence the pathogenic behavior of the bacterium.
Expanding the scope of sampling to include more regions and hosts.
Employing whole-genome sequencing (WGS) for deeper insights into the bacterial genome.
This could pave the way for developing more effective therapeutic strategies.
Division of Media and Governmental Communication – College of Veterinary Medicine – University of Basrah
