The Department of Chemistry, College of science organized a seminar about preparation of a new series of sulfa-quinoline compounds, presented by the M.Sc. Student: Raghad Jawad Kadhum.
The study consisted of two parts:
The first part included the preparation of a new series of sulfa-quinoline compounds from the reaction of quinoline derivatives with a series of sulfa compounds. The reactions were followed up with the technique of (TLC ) and these compounds were diagnosed by (FT-IR,H1 NMR,C13 NMR, Mass Spacta )and the biological activity was studied as an anti-cancer cell line ( MCF-7) and On the other hand, molecular docking results for the synthesized compounds using both MOE and Auto Dock Vina programs, showed that: Compounds QSC ,QSD, QSMBr ,QSMZ and QSP displayed best affinity value among other compound (QST ,QSMT ) respectively and this confirmed with their experimental result.
While the other part of the study included the preparation of a lycand from the reaction of the quinoline derivative with thiocarbazide and the preparation of copper, cobalt and vanadium complexes from it,(QV,QCu ,QCo ) and then the diagnosis of these complexes using the technique of FT-IR ,ESI ,TGA ,Magnetic Sensitivity ,Molar Electrical Conductivity.
