The instructors at the College of Pharmacy at the University of Basrah, Faten Essam Hussein, Prof. Dr. Falah Hassan Shari and Assistant Prof. Dr. Ola Muhammad Nour Al-Moussawi, published a research entitled (In vitro anticancer activity of RA extracts of peppermint leaves against human cancer breast and cervical cancer cells) In the Japanese Teikyo Medical Journal.
The research included studying the efficacy of rosmarinic acid against breast and cervical cancer in vitro.
Agents: Breast cancer (MCF-7 cell line, cervical cancer) cell line (HELA)
As well as studying the anti-cancer effects of phenolic rosmarinic acid extracted and purified from peppermint in vitro. Whereas rosmarinic acid was tested in vitro on breast cancer cells MCF7 at concentrations of 100, 250, 500, 750, 1000 μg/ml and human cervical cancer at concentrations 100, 250, 500 and 1000 µg/ml where rosmarinic acid reduced the activity and growth of breast cancer cells by 48% at a concentration of 1000 µg/ml, while the effect of the acid on the activity of normal cells was only 4% at the same concentration, which gives rosmarinic acid a selective property for breast cancer cells.
As for the cervical cancer cell line, the acid did not show a significant effect on the activity and growth of cancer cells.
