A master's thesis at the College of Medicine, University of Basrah, discussed heat shock protein 70 and protein oxidation in type 2 diabetes mellitus. The research presented by the student Amani Abdel Mohsen Yass aims to compare the levels of heat shock protein HSP70 and PC protein between patients with type 2 diabetes and the control sample, and study the association between them, in addition to studying the association of these two indicators with the lipid pattern. The study also aims to assess the effect of diabetes, blood sugar control, age, body mass index, waist circumference, and type of treatment used in diabetes on the levels of heat shock protein HSP70 and PC. The research concluded that the main result of the current study is that the arithmetic means of the levels of heat shock protein HSP70 and PC protein in the blood serum had a statistically significant higher value in patients with type 2 diabetes when compared with the control sample, and there was a significant positive correlation between their levels in the blood serum. The results also showed that there is an increase in the oxidation of proteins in people with type 2 diabetes by observing the high content of carbonic protein in them, which may play an important role in the development of the disease. The results also revealed that the mean level of heat shock protein HSP70 in the blood serum had a statistically significant higher value in patients with type 2 diabetes who were suffering from a loss of metabolic control over the level of sugar. The positive relationship between the level of HSP70 with the level of fasting blood glucose and glycated hemoglobin indicates that the high level of glucose in the blood may increase the level of HSP70 in the blood serum, which indicates that HSP70 may have a role in the development of diabetes.
