Instructors at the College of Pharmacy at the University of Basrah, Dr. Falah Hassan Shari, Dr. Rafid Abdul-Raouf Dolab, and Dr. Ghassan Salah Ahmad obtained a patent registered in America.
The patent included evaluation of the impurities of elements in medicines according to the pharmacopoeia using electron microscopy technology and energy-dispersive spectrophotometry.
As primary impurities are indispensable in the pharmaceutical industry to ensure the safety of those preparations, for (24) elements despite the use of atomic absorption and inductively coupled plasma in the US Pharmacopoeia and the European Pharmacopoeia, FESEM with energy-dispersive spectrometers can be applied as an alternative analysis method for quantitative results And quality for a variety of items without chemical pre-treatment, unlike other techniques.
This technique is characterized by the shortest time with less contamination, no consumption of the reagent and the generation of minimal residues or waste in addition to limiting the sample preparation time with minimal analysis errors.
This study is the application of FESEM-EDS in the US Pharmacopoeia and ICH/Q3D guidelines with better results than other techniques, because it does not require complex methods or digestion chemicals that interfere with the final results with the possibility of sample retention anywhere. It's time to re-analyze. The recommendation is to use this technique in the pharmacopoeia as standard methods as inductively coupled plasma both ICP-AES, ICP-OES and ICP-MS
