a master’s thesis at the College of Pharmacy at the University of Basrah discussed (synthesis analysis and study of molecular docking and biological evaluation of new coumarin-pyrazoline derivatives).
Researcher Wafaa Youssef Khalaf’s thesis included the manufacture of two groups of coumarin-derived materials. The first group contained coumarin chalcone derivatives, while the second group contained coumarin pyrazolline derivatives. These compounds were then diagnosed using various spectroscopic analyzes such as infrared radiation, mass spectrometry, magnetic resonance spectroscopy, and the use of ultraviolet-visible spectra.
The thesis aims to determine the biological effectiveness using a molecular docking program and biological cells. The thesis concluded that these derivatives work as antioxidants, but they have little biological effectiveness against a special type of breast cancer cell known as MCF7.
