A research team from University of Basrah obtains a patented
Lecturer Zaid Nour Obaid from the Babylon College of Education, Dr. Jassim Muhammad Saleh from the Department of Chemistry, and Dr. Ali Abdul Latif Abdul Hassan from the Department of Life Sciences obtained a patented for the preparation of a tetrahedral nickel (II) complex derived from diamine ginyl and the possibility of using it to treat esophageal cancer (SK- GT-4) and hepatocellular carcinoma (HCAM). The patented included the preparation of a previously unprepared nickel (II) complex with the ligand. The metal complex was prepared in its solid state in a molar ratio of (1:1) by dissolving the weights of each metal salt in (10 ml) of absolute ethanol to the ligand solution dissolved in (30 ml) of the same solvent after completing the mixing process and then performing the sublimation process for a period of time at a temperature that is considered a potential treatment for esophageal cancer and liver cancer. The newly prepared invention in our laboratory proved its effectiveness and pharmacological effect through studying biological and toxicological tests on human cells infected with esophageal cancer, liver cancer, and healthy ones for the purpose of comparison. It was noted that the nickel (II) complex has high effectiveness in inhibiting esophageal cancer cells in humans with a good rate of selectivity when treating tumors. This type of cancer encourages its use as a candidate substance for treating this type of cancer, as the highest rate of inhibition of nickel (II) complexes in esophageal cancer cells was achieved.
