The College of Science at the University of Basrah organized a seminar (The correlation between the biofilm formation genes and antibiotic resistance in Acinetobacter baumannii isolation from hospitalized patients and prepare new compound as antibacterial) by the graduate student Fatima Waleed Abdul-Ameer.
The study aims to determine the biofilm-related genes and their relationship to multi-drug resistance in bacterial isolates, and to prepare the compound "Thiochromene " extracted from garlic. The study included the clinical and molecular identification of the isolates and demonstrated the high inhibitory activity of the extracted compound against the target bacteria. The study recommended expanding the scope of future studies to include larger numbers of clinical isolates from different sources and hospitals and studying the gene expression of the bap gene and other virulence factors of resistant bacterial isolates. Completing research to understand the mechanism of action of Thiochromene and its clinical applications to reduce the spread of resistant bacteria.
