The master's thesis in the College of Pharmacy at Basra University discussed (the preventive effect of some antioxidant preparations on kidney and diabetes disease in rabbits) by researcher Raghda Khalil Tohma. The thesis included diabetic-induced events in fasting rabbits by injecting them with streptozotocin at a dose of 50 mg/kg. Then began treatment with antioxidants for animals, and blood samples were taken every two weeks and laboratory analyzes were performed that included blood sugar, blood urea, serum creatinine, serum electrolyte, and (LDL-c) in serum. Antioxidants were also used in different combinations in the first treatment group and in The second treatment group. The research aims to evaluate the effect of antioxidant factors on testing kidney function in diabetic rabbits. The results of this thesis recorded a significant decrease in blood serum for both urea, creatinine, and LDL-C in the first treatment group and the second treatment group compared to the control group in diabetes, and also a significant increase in the levels of serum potassium and chloride serum in the first treatment group and the second treatment group compared to the control group in the disease. Diabetes. The results of this study demonstrated the role of antioxidants as an adjunctive treatment in reducing and preventing diabetic kidney disease by affecting the reactive oxygen species produced by diabetic kidney tissues.
