The College of Science at the University of Basrah organized a seminar entitled (the effect of PML overexpression on ability of adenovirus to transform cells, Gene Therapy) by the graduate Muayad Ismael Ridha
The study aims The PML protein overexpression of Tumor suppressor factor, this will reduce the effect of virus infection on the gene expression of Rb, which can inhibit the ability of the virus to cellular transformation and included .. Definition of human adenovirus type 5 role to transform cells and role of the PML gene in repressing transformation Retinoblastoma (Rb) is a gene responsible for suppressing uncontrolled cell growth and controlling its division. It is known that this virus has the ability to bind to this protein to inactivate it through a viral protein that is the cause of cellular transformation produced from the early region of the virus genome called E1A oncogenic protein
