The College of Science at the University of Basrah organized a seminar entitled (IgE mediated Hypersensitivity and Asthma)
By the graduate student Mahmoud Sameer Mohamed Nuhad
The study aims to shed light on the role of IgE in inducing the first type of allergy, especially asthma, and how to induce cells, especially Mast cells, Basophils, to release their components and the role of these components in inducing the inflammatory response to asthma.
Hypersensitivity is an undesirable and exaggerated reaction that occurs naturally due to the excessive or exaggerated activity of the immune system towards an allergen. Hypersensitivity requires prior stimulation of the immune system of people predisposed to develop hypersensitivity to some type of allergen.
Gell-Coombs classified hypersensitivity reactions into four types depending on the mechanism and the time it takes for the occurrence and emergence of allergy symptoms to (type I , type II , type III and type IV).
Type I the main substance responsible for initiating and mediating allergic reactions is IgE and the main cellular components in this type of hypersensitivity are mast cells, basophils and the allergic reaction is activated by neutrophils, eosinophils. They include (asthma - eczema - Hay fever - food allergy - bee stings)
