Master’s Thesis at the University of Basrah Explores the Molecular Diagnosis of Proteus mirabilis
A master’s thesis at the College of Veterinary Medicine, University of Basrah, investigated the molecular diagnosis of Proteus mirabilis isolated from humans and domestic animals.
The thesis, conducted by the student Hussein Ali Nasser, aimed to isolate and identify this bacterium from human samples as well as from cats and dogs, employing both conventional and molecular techniques.
The research focused on analyzing four major virulence genes (ureC, hpmA, mrpA, and ureR) to detect genetic diversity and single nucleotide polymorphisms (SNPs) in comparison with a reference strain.
The findings revealed a significant genetic diversity among local isolates, with the identification of SNPs that may influence the pathogenic behavior of the bacterium.
The study recommended expanding the sampling scope and applying whole genome sequencing (WGS) to gain deeper insights into the bacterial genome, thereby paving the way for the development of improved therapeutic strategies.
Department of Media and Governmental Communication
