Master’s Thesis at the University of Basrah Explores the Design of Filters for Kinase Enzyme Inhibition
A master’s thesis at the College of Pharmacy, University of Basrah, investigated the design and synthesis of molecular filters containing amines to enhance the inhibition of kinase enzymes.
The thesis, presented by graduate student Karrar Taleb Awad Hneish, aimed to design and synthesize new thiourea derivatives to evaluate their potential as inhibitors of CDK-2 enzyme, in addition to studying the cytotoxic activity of these compounds on selected cancer cell lines to assess their possible therapeutic effectiveness.
The research included a comprehensive study of thiourea derivatives through a review of related scientific literature on their biological activity, along with the synthesis of a new series of thiourea-based compounds. Their physical and chemical properties were determined using modern spectroscopic analysis techniques.
Department of Media and Governmental Communication
