Master's Thesis at the University of Basrah Examines the Relationship between Leptin and Glucagon Levels in Patients with Diabetic Nephropathy
A master's thesis at the College of Pharmacy at the University of Basrah examined the relationship between leptin and glucagon-like peptide-1 (GLP-1) levels in serum in patients with diabetic nephropathy: a non-interventional case-control study.
The thesis, presented by student Haneen Hisham Fadhel, aimed to evaluate and compare levels of leptin (LEP), glucagon-like peptide-1 (GLP-1), monocyte chemoattractant protein-1 (MCP-1), vitamin D, parathyroid hormone (PTH), blood pressure, and glycated hemoglobin (HbA1c) among patients at different stages of kidney disease and healthy controls, and to determine the predictive value of these markers in the development of kidney failure.
The study found distinct patterns of metabolic and inflammatory biomarkers in the stages of chronic kidney disease, particularly in diabetic patients, with glucagon-like peptide (GLP) and parathyroid hormone (PTH) emerging as strong indicators of disease progression.
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