Ph.D. Dissertation at the University of Basrah Examines the Virulence Analysis of Klebsiella pneumoniae in Living Organisms
A Ph.D. dissertation at the College of Veterinary Medicine, University of Basrah, investigated the virulence analysis, serotypes, and immune response associated with respiratory infections caused by Klebsiella pneumoniae in humans and sheep.
The dissertation, presented by researcher Ali Abd Kazem, aimed to identify Klebsiella pneumoniae in respiratory tract infections, explore the immune response to the bacterium, and analyze the genes responsible for antibiotic resistance, efflux pump systems, virulence factors, biofilm formation, and serotyping.
The study examined 300 suspected cases from humans and sheep, from which 42 positive isolates were obtained. Of these, 17 samples were selected for genome sequencing and subsequently deposited in the NCBI GenBank database.
The dissertation recommended applying whole-genome sequencing (WGS) techniques to other local isolates to contribute to the development of effective therapeutic and preventive strategies.
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