Master's Thesis at the University of Basrah Investigates the Enhanced Effect of Valproic Acid and Melatonin on the Liver
A master's thesis at the College of Pharmacy, University of Basrah, investigated the enhanced effect of valproic acid and melatonin, and their synergistic effect, in paracetamol-induced liver injury in rats.
The thesis, submitted by student Huda Iyad Haider, aimed to evaluate and compare the protective effects of valproic acid, melatonin, and their combination against paracetamol-induced liver damage in rats.
The thesis comprised four chapters in which the student discussed paracetamol-induced liver injury as a model of drug-induced hepatotoxicity, focusing on the role of oxidative stress and inflammation as key mechanisms of liver damage.
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