PhD Dissertation at the University of Basrah Explores the Anticancer and Antioxidants Effects on Humans
A PhD dissertation at the College of Veterinary Medicine, University of Basrah, investigated "Functional and Molecular Evaluation of Biosynthesized Silver Nanoparticles (Green Method) Using Momordica Carnitia Fruit: Anticancer Activity Against Human Anaplastic Thyroid Cancer (In Vitro) and Antioxidant Protection Against Thyroid Dysfunction (In Vivo)."
The study, presented by researcher Sumaya Farouk Qasim, aimed to investigate the effects of both the methanolic extract of Momordica Carnitia fruit and biosynthesized silver nanoparticles from the same fruit on human anaplastic thyroid cancer cell lines and gene expression of a gene associated with this type of cancer (in vitro), as well as on thyroid dysfunction (in vivo).
The study concluded that environmentally friendly, manufactured silver nanoparticles extracted from Momordica carrantia fruit exhibited anticancer effects in vitro compared to the crude extract of the fruit, in addition to their effectiveness in significantly inhibiting the gene expression of a cancer-causing gene. Furthermore, the methanolic extract of Momordica carrantia fruit and the silver nanoparticles from the same fruit effectively restored thyroid function and antioxidant balance.
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