Master's thesis at University of Basrah examines the anti-inflammatory effects of famotidine treatment
A master's thesis at College of Pharmacy at University of Basrah examined the anti-inflammatory effects of famotidine treatment in a model of respiratory tract inflammation in rats.
The thesis submitted by the student Wasan Ali Hassan aims to study the role of famotidine in treating some respiratory inflammatory diseases in rats and compare it with prednisolone treatment.
The results showed that famotidine exhibits anti-inflammatory effects compared to prednisolone for inflammation in the airways of rats, as it was shown to reduce the production of cytokines (TNF-α and IL-6) and inhibit the activation of immune cells (eosinophils, neutrophils and monocytes) and alleviate damage to lung tissue caused by inflammation.
The results indicated that famotidine may have potential therapeutic applications beyond its primary use for treating heartburn.
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